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[PubMed] [Google Scholar] 4.Vitamin B12 deficiency - a 21st century perspective

Davydov AI, Khabarova MB, Chilova RA, Lebedev VA, Shakhlamova MN

Chem - Eur J

While GLP-1 and GIP signalling primarily enhance insulin secretion and modulate appetite, glucagon receptor activation increases hepatic glucose output, stimulates lipolysis in adipose tissue, and promotes thermogenesis

Then PLS-DA and OPLS-DA were carried out with 72 metabolites as X variables and 90 serum samples as Y variables, and modeling parameters R2Y and Q 2 were used to evaluate the model